Article
Megacystis-microcolon-intestinal hypoperistalsis syndrome and the absence of the alpha3 nicotinic acetylcholine receptor subunit.
Gastroenterology - 1 Aug 2001
Richardson C E, Morgan J M, Jasani B, Green J T, Rhodes J, Williams G T, Lindstrom J, Wonnacott S, Thomas G A, Smith V
Abstract excerpt
BACKGROUND & AIMS: The megacystis-microcolon-intestinal hypoperistalsis syndrome (MMIHS) is a rare disease of childhood that presents early with intestinal hypoperistalsis, hydronephrosis, and hydroureters. Transgenic mice that lack the alpha3 subunit containing nicotinic acetylcholine (nAChR) ha...
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