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Article

SHH mutation is associated with solitary median maxillary central incisor: a study of 13 patients and review of the literature.

American journal of medical genetics - 22 Jul 2001

Nanni L, Ming J E, Du Y, Hall R K, Aldred M, Bankier A, Muenke M

Abstract excerpt

Solitary median maxillary central incisor (SMMCI) or single central incisor is a rare dental anomaly. It has been reported in holoprosencephaly (HPE) cases with severe facial anomalies or as a microform in autosomal dominant HPE (ADHPE). In our review of the literature, we note that SMMCI may also occur as an isolated finding or in association with other systemic abnormalities. These anomalies include short...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11471164
DOI: 10.1002/1096-8628(20010722)102:1<1::aid-ajmg1336>3.0.co;2-u

Genes

SHH
SIX3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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