Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bile salt export pump is highly conserved during vertebrate evolution and its expression is inhibited by PFIC type II mutations.

American journal of physiology. Gastrointestinal and liver physiology - 1 Aug 2001

Cai S Y, Wang L, Ballatori N, Boyer J L

Abstract excerpt

Bile secretion is a fundamental function of the liver of all vertebrates and is generated by ATP-dependent transport proteins at the canalicular membrane of hepatocytes, particularly by the bile salt export pump BSEP. To determine the evolutionary origin and structure-function relationship of thi...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ATP Binding Cassette Transporter, Subfamily B, Member 11
Share to ATP-Binding Cassette Transporters

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Biological Transport

Share to Cholestasis, Intrahepatic

Share to Conserved Sequence

Share to Sequence Homology, Amino Acid

Share to Spodoptera

Source

Identifiers

PMID: 11447010
DOI: 10.1152/ajpgi.2001.281.2.G316

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11447010-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bile salt export pump is highly conserved during vertebrate evolution and its expression is inhibited by PFIC type II mutations.PMID 11447010Read ↗

Recent advances in the exploration of the bile salt export pump (BSEP/ABCB11) function.Semantic proximity Read ↗

Biosynthesis and trafficking of the bile salt export pump, BSEP: therapeutic implications of BSEP mutations.Semantic proximity Read ↗

Bile salt export pump (BSEP/ABCB11): trafficking and sorting disturbances.Semantic proximity Read ↗

The bile salt export pump: clinical and experimental aspects of genetic and acquired cholestatic liver disease.Semantic proximity Read ↗

A novel mutation within a transmembrane helix of the bile salt export pump (<scp>BSEP</scp>,<i><scp>ABCB</scp>11</i>) with delayed development of cirrhosisSemantic proximity Read ↗

The role of the sodium-taurocholate cotransporting polypeptide (NTCP) and of the bile salt export pump (BSEP) in physiology and pathophysiology of bile formation.Semantic proximity Read ↗

The bile salt export pump (BSEP) in health and diseaseSemantic proximity Read ↗

Role of the bile salt export pump, BSEP, in acquired forms of cholestasis.Semantic proximity Read ↗

The Bile Salt Export Pump: Molecular Structure, Study Models and Small-Molecule Drugs for the Treatment of Inherited BSEP Deficiencies.Semantic proximity Read ↗

The role of bile salt export pump mutations in progressive familial intrahepatic cholestasis type IISemantic proximity Read ↗

Canalicular ABC transporters and liver disease.Semantic proximity Read ↗

Hepatocanalicular bile salt export pump deficiency in patients with progressive familial intrahepatic cholestasis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.