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Article

Plasticity of fitness and diversification process during an experimental molecular evolution.

Journal of molecular evolution - 1 Jun 2001

Kashiwagi A, Noumachi W, Katsuno M, Alam M T, Urabe I, Yomo T

Abstract excerpt

A simplified experimental evolution encompassing the essence of natural one was designed in an attempt to understand the involved mechanism. In our system, molecular evolution was observed through three serial cycles of consecutive random mutagenesis of the glutamine synthetase gene and chemostat culture of the transformed Escherichia coli cells containing the mutated genes. Selection pressure was imposed solely...

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PMID: 11443353
DOI: 10.1007/s002390010180

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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