Article
Role of the response regulator RssB in sigma recognition and initiation of sigma proteolysis in Escherichia coli.
Molecular microbiology - 1 Jun 2001
Klauck E, Lingnau M, Hengge-Aronis R
Abstract excerpt
In growing Escherichia coli cells, the master regulator of the general stress response, sigmaS (RpoS), is subject to rapid proteolysis. In response to stresses such as sudden carbon starvation, osmotic upshift or shift to acidic pH, sigmaS degradation is inhibited, sigmaS accumulates and numerous sigmaS-dependent genes with stress-protective functions are activated. sigmaS proteolysis is dependent on ClpXP...
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