Article
New-generation proton pump inhibitors: overcoming the limitations of early-generation agents.
European journal of gastroenterology & hepatology - 1 May 2001
Robinson M
Abstract excerpt
Proton pump inhibitors (PPIs) are now generally considered the drugs of choice for treatment of patients with serious or refractory acid-related diseases. However, despite some popular notions to the contrary, these agents are not equivalent in their pharmacokinetic, pharmacodynamic and efficacy profiles. When the two newest PPIs, rabeprazole and esomeprazole, are compared with the older drugs in this class...
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