Article
Linked markers exclude KIT as the gene responsible for appaloosa coat colour spotting patterns in horses.
Animal genetics - 1 Apr 2001
Terry R R, Bailey E, Bernoco D, Cothran E G
Abstract excerpt
The appaloosa coat colour pattern of the horse is similar to that caused by the rump-white (Rw) gene in the mouse. In the mouse Rw colour pattern is the result of an inversion involving the proto-oncogene c-kit (KIT). Therefore, we investigated KIT as a candidate gene that encodes the appaloosa coat colour gene (Lp) in horses. KIT plays a critical role in haematopoiesis, gametogenesis, and melanogenesis and...
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