Article
Neural change in Trichinella-infected mice is MHC II independent and involves M-CSF-derived macrophages.
American journal of physiology. Gastrointestinal and liver physiology - 1 Jul 2001
Galeazzi F, Lovato P, Blennerhassett P A, Haapala E M, Vallance B A, Collins S M
Abstract excerpt
Intestinal inflammation due to nematode infection impairs enteric cholinergic nerve function and induces hypercontractility of intestinal muscle. Macrophages have been implicated in the neural changes, but the subpopulation and mechanism involved are unknown. We examined whether macrophages alter nerves by virtue of their ability to activate lymphocytes via major histocompatibility complex (MHC) II-restricted...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.