Article
Coordinate gene regulation by fimbriae-induced signal transduction.
The EMBO journal - 15 Jun 2001
Schembri M A, Klemm P
Abstract excerpt
Fimbriae are thread-like polymers displayed in large amounts on the bacterial surface and used by many pathogens to attach to receptors on host tissue surfaces. Fimbriae contain disulfide bridges, contrary to many Escherichia coli surface proteins produced in bulk amounts. Here we investigate whether fimbriae expression can affect expression of other genes. Analysis of gene expression in two E.coli strains,...
Topics
- Adhesins, Bacterial
- Adhesins, Escherichia coli
- Antigens, Bacterial
- Bacterial Outer Membrane Proteins
- DNA-Binding Proteins
- Disulfides
- Dithiothreitol
- Escherichia coli
- Escherichia coli Proteins
- Fimbriae, Bacterial
- Gene Expression Regulation, Bacterial
- Multigene Family
- Phenotype
- Repressor Proteins
- Signal Transduction
- Transcription Factors
- Transcription, Genetic
