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Article

Role of activin A in negative regulation of normal and tumor B lymphocytes

1 Jun 2001

Abstract excerpt

Activin A, a member of the transforming growth factor beta superfamily, has a wide spread expression pattern and pleiotropic functions. In this overview we summarize data that points to a role of activin A in negative regulation of B lineage lymphocytes. Experiments performed by us and by other groups revealed the capacity of activin A to cause apoptotic death of tumor myeloma cells, through mechanisms of cell...

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Identifiers

PMID: 11404369
DOI: 10.1189/jlb.69.6.867

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