Amphetamine and cocaine induce different patterns of c‐<i>fos</i> mRNA expression in the striatum and subthalamic nucleus depending on environmental context

Abstract excerpt

In the dorsal striatum, there are two major populations of medium spiny projection neurons. One population is positive for dynorphin mRNA (DYN+), and these cells project preferentially to the substantia nigra, forming the so-called 'direct pathway'. A second population is positive for enkephalin mRNA (ENK+), and these cells influence the substantia nigra indirectly, via the globus pallidus and subthalamic...

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