Article
Inverse Correlation between Sperm Concentration and Number of Androgen Receptor CAG Repeats in Normal Men<sup>1</sup>
1 Jun 2001
Abstract excerpt
Androgens are essential for the maintenance of normal spermatogenesis. Androgen action is mediated by the androgen receptor (AR), which in the testis is expressed by Leydig, peritubular, and Sertoli cells. The fact that sperm numbers range from 20 up to 300 million/mL in normal men without any indication of changed endocrine parameters led us to assume that genetic variability of transduction of androgen...
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