Article
Vitamin D receptor gene polymorphisms, insulin-like growth factors, and prostate cancer risk: a population-based case-control study in China.
Cancer research - 1 Jun 2001
Chokkalingam A P, McGlynn K A, Gao Y T, Pollak M, Deng J, Sesterhenn I A, Mostofi F K, Fraumeni J F, Hsing A W
Abstract excerpt
Operating through the vitamin D receptor (VDR), vitamin D inhibits prostate cancer growth and increases insulin-like growth factor binding protein (IGFBP) expression, suggesting that the vitamin D and insulin-like growth factor (IGF) regulatory systems may operate together to affect prostate cancer. Among 191 newly diagnosed prostate cancer cases and 304 randomly selected population controls in Shanghai, China,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.