Article
Lack of association between vitamin D receptor gene FokI and BsmI polymorphisms and prostate cancer risk: an updated meta-analysis involving 21,756 subjects.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Oct 2013
Guo Zhan, Wen Jianguo, Kan Quancheng, Huang Shuman, Liu Xianghua, Sun Ning, Li Zhenzhen
Abstract excerpt
The vitamin D receptor (VDR) is a crucial mediator for the cellular effects of vitamin D. The polymorphisms in the VDR gene have been hypothesized to alter the risk of prostate cancer. However, studies investigating the association between VDR polymorphisms (BsmI and FokI) and prostate cancer (PCa) risk report conflicting results , therefore, we conducted a meta-analysis to re-examine the controversy. Published...
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