Article
Neurodevelopmental indices and the development of psychotic symptoms in subjects at high risk of schizophrenia.
The British journal of psychiatry : the journal of mental science - 1 Jun 2001
Lawrie S M, Byrne M, Miller P, Hodges A, Clafferty R A, Cunningham Owens D G, Johnstone E C
Abstract excerpt
BACKGROUND: Neurological 'soft signs' and minor physical anomalies (MPAs) are reported to be more frequent in patients with schizophrenia than in controls. AIMS: To determine whether these disturbances are genetically mediated, and whether they are central to the genesis of symptoms or epiphenomena. METHOD: We obtained ratings in 152 individuals who were antipsychotic drug-free and at high risk, some of whom had...
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