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Article

Neurological soft signs in non-psychotic first-degree relatives of patients with schizophrenia: a systematic review and meta-analysis.

Neuroscience and biobehavioral reviews - 1 May 2010

Chan Raymond C K, Xu Ting, Heinrichs R Walter, Yu Yue, Gong Qi-yong

Abstract excerpt

BACKGROUND: Neurological soft signs (NSS) have been associated with the neuropsychopathology of schizophrenia, and have been proposed as candidate endophenotypes for this clinical group. However, the prevalence rate of NSS in non-psychotic first-degree relatives is not fully known. The authors systematically and quantitatively reviewed the literature to determine the magnitude of difference between: (1)...

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PMID: 19925825
DOI: 10.1016/j.neubiorev.2009.11.012

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