Physical manifestations of neurodevelopmental disruption: are minor physical anomalies part of the syndrome of schizophrenia?

doi:10.1093/schbul/sbn151

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Article

Physical manifestations of neurodevelopmental disruption: are minor physical anomalies part of the syndrome of schizophrenia?

Schizophrenia bulletin - 1 Mar 2009

Compton Michael T, Walker Elaine F

Abstract excerpt

The well-documented excess of minor physical anomalies (MPAs) among individuals with schizophrenia generally supports the neurodevelopmental model, which posits that both genetic and environmental factors contribute to structural and functional brain changes in the intrauterine and perinatal periods that predispose one to developing schizophrenia. This review synthesizes select areas of research findings on MPAs...

Topics

Biomarkers
Cognition Disorders
Congenital Abnormalities
Craniofacial Abnormalities
Epigenesis, Genetic
Female
Humans
Male
Mutation
Phenotype
Risk Factors
Schizophrenia
Syndrome

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Identifiers

PMID: 18990714
DOI: 10.1093/schbul/sbn151
PMCID: PMC2659308

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