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Article

Genetic bottlenecks, perceived racism, and hypertension risk among African Americans and first-generation African immigrants.

Journal of human hypertension - 1 May 2001

Poston W S, Pavlik V N, Hyman D J, Ogbonnaya K, Hanis C L, Haddock C K, Hyder M L, Foreyt J P

Abstract excerpt

The complexity of factors influencing the development of hypertension (HTN) in African Americans has given rise to theories suggesting that genetic changes occurred due to selection pressures/genetic bottleneck effects (ie, constriction of existing genetic variability) over the course of the slave trade. Ninety-nine US-born and 86 African-born health professionals were compared in a cross-sectional survey...

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Identifiers

PMID: 11378837
DOI: 10.1038/sj.jhh.1001174

Genes

AGT
ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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