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Article

NucA is required for DNA cleavage during transformation of Bacillus subtilis.

Molecular microbiology - 1 May 2001

Provvedi R, Chen I, Dubnau D

Abstract excerpt

We have re-examined the roles of nucA and nin, in the transformation of Bacillus subtilis as conflicting accounts have been presented concerning the importance of these genes for transformation. The present report demonstrates that nucA deficiency lowers the rate of DNA transport and that NucA is needed for the double-strand cleavage of transforming DNA, probably acting directly as an endonuclease. A relative...

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PMID: 11359569
DOI: 10.1046/j.1365-2958.2001.02406.x

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