Article
Anxiety-related behaviors in the elevated zero-maze are affected by genetic factors and retinal degeneration.
Behavioral neuroscience - 1 Apr 2001
Cook M N, Williams R W, Flaherty L
Abstract excerpt
Anxiety levels were tested in an elevated zero-maze for 8 inbred strains of mice that are used widely in biomedical and behavioral research. Strain differences were observed for activity, latency to enter an open quadrant, open time, and defecation, demonstrating that genetic factors mediate anxiety in this paradigm. Three of the strains have the rdl mutation that causes retinal degeneration and were less anxious...
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