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Article

Gap-junctional communication is required for the maturation process of osteoblastic cells in culture.

Bone - 1 Apr 2001

Schiller P C, D'Ippolito G, Balkan W, Roos B A, Howard G A

Abstract excerpt

Osteoblastic cells in long-term culture undergo a phenotypic maturation process leading to extracellular matrix (ECM) production and bone nodule (BN) formation. Cell-to-cell communication via gap junctions (GJC) can be detected between osteoblastic cells within 24 h of plating. We evaluated, in long-term cultures of osteoblastic cells, the effect of inhibiting GJC on the phenotypic maturation process and the...

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PMID: 11336916
DOI: 10.1016/s8756-3282(00)00458-0

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AGA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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