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A massive systematic infection of Encephalitozoon cuniculi genotype III in mice does not cause clinical signs.

Microbes and infection - 1 Oct 2020

Sak Bohumil, Brdíčková Klára, Holubová Nikola, Květoňová Dana, Hlásková Lenka, Kváč Martin

Abstract excerpt

Encephalitozoon cuniculi genotype III disseminated intensively into most of the organs in all strains of mice, followed by a chronic infection with massive microsporidia persistence in immunodeficient mice and a partial decrease in C57Bl/6 mice. Treatment with 0.2 mg Albendazole/mouse/day temporarily reduces the number of affected organs in immunocompetent C57Bl/6 mice, but not in CD4-/- and CD8-/- mice. The...

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PMID: 32579904
DOI: 10.1016/j.micinf.2020.06.004

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