Endpoints and surrogates for use in population studies in toxicology.

doi:10.1016/s0378-4274(01)00271-5

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Article

Endpoints and surrogates for use in population studies in toxicology.

Toxicology letters - 31 Mar 2001

Greim H

Abstract excerpt

Risk characterisation of human exposure to chemicals requires information on the intrinsic toxic (hazardous) properties of the chemical, dose response of effects for the critical endpoints and exposure of the population. Information on hazardous properties, including data on mechanism and toxicokinetics, is necessary to define the critical endpoints and the relevant parameters to assess internal exposure and its...

Topics

DNA Adducts
Demography
Environmental Exposure
Genetic Predisposition to Disease
Lymphocytes
Polymorphism, Genetic
Risk Assessment
Toxicology
Xenobiotics

Source

Open in PubMed

Identifiers

PMID: 11323199
DOI: 10.1016/s0378-4274(01)00271-5

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