Article
Estimating divergence time with the use of microsatellite genetic distances: impacts of population growth and gene flow.
Molecular biology and evolution - 1 May 2001
Zhivotovsky L A
Abstract excerpt
Genetic distances play an important role in estimating divergence time of bifurcated populations. However, they can be greatly affected by demographic processes, such as migration and population dynamics, which complicate their interpretation. For example, the widely used distance for microsatellite loci, (deltamu)2, assumes constant population size, no gene flow, and mutation-drift equilibrium. It is shown here...
Topics
- Animals
- Genetic Markers
- Genetic Variation
- Geography
- Hominidae
- Humans
- Mathematics
- Microsatellite Repeats
- Models, Genetic
- Models, Statistical
- Mutagenesis
- Mutation
- Polymorphism, Genetic
- Population Growth
- Tandem Repeat Sequences