Article
Usefulness of microsatellite typing in population genetic studies of Trypanosoma cruzi.
Memorias do Instituto Oswaldo Cruz - 1 Apr 2001
Macedo A M, Pimenta J R, Aguiar R S, Melo A I, Chiari E, Zingales B, Pena S D, Oliveira R P
Abstract excerpt
Through microsatellite analysis of 53 monoclonal populations of Trypanosoma cruzi, we found a remarkable degree of genetic polymorphism with no single multilocus genotype being observed more than once. The microsatellite profile proved to be stable during 70 generations of the CL Brener clone in culture. The microsatellite profiling presented also high diagnostic sensitivity since DNA amplifications could be...
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