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A Korean family with a dominantly inherited beta-thalassemia due to Hb Durham-N.C./Brescia.

Hemoglobin - 1 Feb 2001

Kim J Y, Park S S, Yang S H, Joo S I, Lee Y J, Ra E K, Shin S, Kim E C, Cho H I

Abstract excerpt

We describe the molecular and the hematological characteristics of a Korean family with a dominantly inherited beta-thalassemia. Carriers were characterized by moderate anemia, hypochromia, microcytosis, elevated Hb A2 and Hb F levels, and splenomegaly. DNA analysis revealed a CTG (Leu) to CCG (Pro) substitution at codon 114 of the beta-globin gene, that leads to a highly unstable hemoglobin variant, Hb...

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Identifiers

PMID: 11300352
DOI: 10.1081/hem-100103072

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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