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Functionally Different AU- and G-rich cis-Elements Confer Developmentally Regulated mRNA Stability inTrypanosoma cruzi by Interaction with Specific RNA-binding Proteins

1 May 2001

Abstract excerpt

Post-transcriptional regulatory mechanisms have been suggested to be the main point of control of gene expression in kinetoplastid parasites. We have previously shown that Trypanosoma cruzi SMUG mucin mRNA steady-state level is developmentally regulated by post-transcriptional mechanisms, being stable in the epimastigote insect vector stage, but unstable in the trypomastigote infective stage of the parasite. Its...

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PMID: 11278796
DOI: 10.1074/jbc.m010959200

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