Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

J-domain protein, Jac1p, of yeast mitochondria required for iron homeostasis and activity of Fe-S cluster proteins.

The Journal of biological chemistry - 18 May 2001

Kim R, Saxena S, Gordon D M, Pain D, Dancis A

Abstract excerpt

J-proteins are molecular chaperones with a characteristic domain predicted to mediate interaction with Hsp70 proteins. We have previously isolated yeast mutants of the mitochondrial Hsp70, Ssq1p, in a genetic screen for mutants with altered iron homeostasis. Here we describe the isolation of muta...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aconitate Hydratase
Share to Hemeproteins
Share to HSP70 Heat-Shock Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Iron-Sulfur Proteins

Share to Mitochondrial Proteins

Share to Molecular Chaperones

Share to Succinate Dehydrogenase

Source

Identifiers

PMID: 11278728
DOI: 10.1074/jbc.M010695200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11278728-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

J-domain protein, Jac1p, of yeast mitochondria required for iron homeostasis and activity of Fe-S cluster proteins.PMID 11278728Read ↗

Characterization of the interaction between the J-protein Jac1p and the scaffold for Fe-S cluster biogenesis, Isu1p.Semantic proximity Read ↗

Iron-Sulfur Cluster Biogenesis Chaperones: Evidence for Emergence of Mutational Robustness of a Highly Specific Protein-Protein Interaction.Semantic proximity Read ↗

Compensation for a defective interaction of the hsp70 ssq1 with the mitochondrial Fe-S cluster scaffold isu.Semantic proximity Read ↗

The mitochondrial proteins Ssq1 and Jac1 are required for the assembly of iron sulfur clusters in mitochondria.Semantic proximity Read ↗

The Hsp70 chaperone Ssq1p is dispensable for iron-sulfur cluster formation on the scaffold protein Isu1p.Semantic proximity Read ↗

Loss of cardiolipin leads to perturbation of mitochondrial and cellular iron homeostasis.Semantic proximity Read ↗

The specialized cytosolic J-protein, Jjj1, functions in 60S ribosomal subunit biogenesis.Semantic proximity Read ↗

Network of general and specialty J protein chaperones of the yeast cytosol.Semantic proximity Read ↗

The functional interaction of mitochondrial Hsp70s with the escort protein Zim17 is critical for Fe/S biogenesis and substrate interaction at the inner membrane preprotein translocase.Semantic proximity Read ↗

Leucine biosynthesis regulates cytoplasmic iron-sulfur enzyme biogenesis in an Atm1p-independent manner.Semantic proximity Read ↗

Mutations in the yeast Hsp40 chaperone protein Ydj1 cause defects in Axl1 biogenesis and pro-a-factor processing.Semantic proximity Read ↗

Dual localized AtHscB involved in iron sulfur protein biogenesis in Arabidopsis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.