Article
HELLP syndrome and factor V Leiden.
European journal of obstetrics, gynecology, and reproductive biology - 1 Mar 2001
Bozzo M, Carpani G, Leo L, Marcozzi S, Sacchi E, Moroni G, Pardi G
Abstract excerpt
The association of thrombophilia and obstetrical complications is documented and well consistent with the hypothesis of an insufficient placental perfusion due to fibrin deposition as a major underlying pathophysiological mechanism. Factor V Leiden is one of the most frequent thrombophilic mutations. A high prevalence of this mutation has recently been reported in a group of 21 German women with haemolysis,...
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