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Article

Genetic aspects of preeclampsia and the HELLP syndrome.

Journal of pregnancy - 1 Jan 2014

Haram Kjell, Mortensen Jan Helge, Nagy Bálint

Abstract excerpt

Both preeclampsia and the HELLP syndrome have their origin in the placenta. The aim of this study is to review genetic factors involved in development of preeclampsia and the HELLP syndrome using literature search in PubMed. A familial cohort links chromosomes 2q, 5q, and 13q to preeclampsia. The chromosome 12q is coupled with the HELLP syndrome. The STOX1 gene, the ERAP1 and 2 genes, the syncytin envelope gene,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24991435
DOI: 10.1155/2014/910751
PMCID: PMC4060423

Genes

ACE
ERAP1
MTHFR
STOX1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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