Article
RGD tripeptide of bluetongue virus VP7 protein is responsible for core attachment to Culicoides cells.
Journal of virology - 1 Apr 2001
Tan B H, Nason E, Staeuber N, Jiang W, Monastryrskaya K, Roy P
Abstract excerpt
Bluetongue virus (BTV) is an arthropod-borne virus transmitted by Culicoides species to vertebrate hosts. The double-capsid virion is infectious for Culicoides vector and mammalian cells, while the inner core is infectious for only Culicoides-derived cells. The recently determined crystal structure of the BTV core has revealed an accessible RGD motif between amino acids 168 to 170 of the outer core protein VP7,...
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