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Impact of VP2 structure on antigenicity: comparison of BTV1 and the highly virulent BTV8 serotype

25 Sept 2024

Abstract excerpt

ABSTRACT Bluetongue virus (BTV) is an agriculturally and economically significant insect-borne virus that causes serious illness and death in sheep and other domestic and wild ruminants in large areas of the world. Numerous BTV serotypes exist, and distant serotypes exhibit unique neutralizing antibody profiles, which target the outermost capsid protein VP2. The predominant serotype-specific nature of the...

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PMID: 39320096
DOI: 10.1128/jvi.00953-24

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