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Article

Increased risk for ischaemic events is related to combined RAS polymorphism.

Heart (British Cardiac Society) - 1 Apr 2001

van Geel P P, Pinto Y M, Zwinderman A H, Henning R H, van Boven A J, Jukema J W, Bruschke A V, Kastelein J J, van Gilst W H

Abstract excerpt

OBJECTIVE: To determine whether the angiotensin converting enzyme (ACE) and the angiotensin II type 1 receptor (AT(1)R A1166C) gene polymorphism interact to increase the risk of ischaemic events, and whether this can be explained by the progression of angiographically defined coronary atherosclerosis. DESIGN: Prospective defined substudy of the lipid lowering regression trial (REGRESS). SETTING: University...

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Source

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Identifiers

PMID: 11250978
DOI: 10.1136/heart.85.4.458
PMCID: PMC1729671

Genes

ACE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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