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Article

High-performance multiplex SNP analysis of three hemochromatosis-related mutations with capillary array electrophoresis microplates.

Genome research - 1 Mar 2001

Medintz I, Wong W W, Berti L, Shiow L, Tom J, Scherer J, Sensabaugh G, Mathies R A

Abstract excerpt

An assay is described for high-throughput single nucleotide polymorphism (SNP) genotyping on a microfabricated capillary array electrophoresis (CAE) microchip. The assay targets the three common variants at the HFE locus associated with the genetic disease hereditary hemochromatosis (HHC). The assay employs allele-specific PCR (ASPCR) for the C282Y (845g->a), H63D (187c->g), and S65C (193a->t) variants using...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Nucleic Acid Amplification Techniques

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Source

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Identifiers

PMID: 11230165
DOI: 10.1101/gr.164701
PMCID: PMC311034

Genes

HFE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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