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Article

Loss of oxidation-reduction specificity in amyotrophic lateral sclerosis-associated CuZnSOD mutants.

Journal of molecular neuroscience : MN - 1 Oct 2000

Cafe C, Testa M P, Sheldon P J, French W P, Ellerby L M, Bredesen D E

Abstract excerpt

Both transgenic mouse and cell culture models of familial amyotrophic lateral sclerosis (FALS) support a gain-of-function effect for the mutations in copper-zinc superoxide dismutase (CuZnSOD) associated with FALS, but the nature of the function gained remains incompletely characterized. We previ...

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Source

Identifiers

PMID: 11220787
DOI: 10.1385/JMN:15:2:71

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11220787-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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