Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DNA methylation contributes to tissue- and allele-specific expression of the T-cell differentiation marker RT6.

Immunogenetics - 1 Jan 2001

Rothenburg S, Koch-Nolte F, Thiele H G, Haag F

Abstract excerpt

We investigated the role of DNA methylation in gene regulation of the rat T-cell differentiation marker RT6. Analysis of the methylation status of various tissues revealed that the RT6 promoter was hypomethylated in RT6-expressing tissues, and methylated in nonexpressing ones. Remarkably, among RT6-nonexpressing tissues, the extent of methylated regions varied greatly between lymphatic tissues, where regions...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ADP Ribose Transferases
Share to Antigens, Differentiation, T-Lymphocyte

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Azacitidine

Share to B-Lymphocytes

Share to Gene Silencing

Share to Organ Specificity

Share to Rats, Inbred Lew

Share to Transcriptional Activation

Source

Identifiers

PMID: 11220625
DOI: 10.1007/s002510000267

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

DNA methylation contributes to tissue- and allele-specific expression of the T-cell differentiation marker RT6.PMID 11220625Read ↗

DNA methylation and Z-DNA formation as mediators of quantitative differences in the expression of alleles.Semantic proximity Read ↗

Independent integration of rodent identifier (ID) elements into orthologous sites of some RT6 alleles of Rattus norvegicus and Rattus rattus.Semantic proximity Read ↗

Nucleotide and deduced amino acid sequence for the mouse homologue of the rat T-cell differentiation marker RT6.Semantic proximity Read ↗

Polymorphic microsatellite within the main promoter of the rat T cell differentiation antigen RT6 on chromosome 1.Semantic proximity Read ↗

Expression of the ectoenzyme RT6 is not restricted to resting peripheral T cells and is differently regulated in normal peripheral T cells, intestinal IEL, and NK cells.Semantic proximity Read ↗

Differential regulation of MHCII genes by PRMT6, via an AT-hook motif of RFX5.Semantic proximity Read ↗

Mutation of a putative TATA motif does not affect transcription by the promoter of the rat T cell differentiation marker RT6.Semantic proximity Read ↗

Evidence that allelic variations in the main RT6 promoter modulate transcriptional activity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.