Article
Two cases of non-Hodgkin's lymphoma in first degree relatives.
Japanese journal of clinical oncology - 1 Dec 2000
Ota I, Shinohara K, Muraki K, Fukuda N, Takahashi T, Nawata R, Shimohakamada Y
Abstract excerpt
Two cases of non-Hodgkin's lymphoma (NHL) generated within 6 months in first degree relatives, a father and a son, are presented. The NHL was a diffuse large B-cell type in the father and a small cleaved follicular type in the son. Cytogenetic and molecular studies of the lymphoma cells revealed the rearrangement of the immunoglobulin heavy chain (JH) gene in both patients, the mutation of p53 gene in the father...
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