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Article

DGGE analysis of the coproporphyrinogen oxidase gene: two new mutations in DNA from Danish patients with hereditary coproporphyria.

Scandinavian journal of clinical and laboratory investigation - 1 Nov 2000

Petersen N E, Käehne M, Christiansen L, Brock A, Hother-Nielsen O, Rasmussen K

Abstract excerpt

The knowledge of at least 21 different mutations and several polymorphisms in the coproporphyrinogen oxidase (CPO) gene demonstrates that the molecular basis of hereditary coproporphyria is heterogeneous. We developed a DGGE-based assay for the analysis of exons 2 to 7, including 14-96 nucleotides of the flanking intronic sequences of the CPO gene. To render it suitable for the clinical diagnostic laboratory, we...

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Source

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PMID: 11202054
DOI: 10.1080/003655100448374

Genes

CPO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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