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Article

RAD50 function is essential for telomere maintenance in Arabidopsis.

Proceedings of the National Academy of Sciences of the United States of America - 13 Feb 2001

Gallego M E, White C I

Abstract excerpt

We have identified and characterized an Arabidopsis thaliana rad50 mutant plant containing a T-DNA insertion in the AtRAD50 gene and showing both meiotic and DNA repair defects. We report here that rad50/rad50 mutant cells show a progressive shortening of telomeric DNA relative to heterozygous ra...

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Identifiers

PMID: 11172016
DOI: 10.1073/pnas.98.4.1711
PMCID: PMC29322

Genes

RAD50

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11172016-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

RAD50 function is essential for telomere maintenance in Arabidopsis.PMID 11172016Read ↗

Meiotic defects in the Arabidopsis rad50 mutant point to conservation of the MRX complex function in early stages of meiotic recombination.Semantic proximity Read ↗

Two roles for Rad50 in telomere maintenance.Semantic proximity Read ↗

The Arabidopsis AtRAD51 gene is dispensable for vegetative development but required for meiosis.Semantic proximity Read ↗

ATM and ATR make distinct contributions to chromosome end protection and the maintenance of telomeric DNA in Arabidopsis.Semantic proximity Read ↗

Alteration of telomeric sequences and senescence caused by mutations in RAD50 of Saccharomyces cerevisiae.Semantic proximity Read ↗

Arabidopsis Rad51B is important for double-strand DNA breaks repair in somatic cells.Semantic proximity Read ↗

Arabidopsis RAD51C gene is important for homologous recombination in meiosis and mitosis.Semantic proximity Read ↗

The AtRAD51C gene is required for normal meiotic chromosome synapsis and double-stranded break repair in Arabidopsis.Semantic proximity Read ↗

A homolog of ScRAD5 is involved in DNA repair and homologous recombination in Arabidopsis.Semantic proximity Read ↗

Homologous recombination in planta is stimulated in the absence of Rad50.Semantic proximity Read ↗

ATR regulates a G2-phase cell-cycle checkpoint in Arabidopsis thaliana.Semantic proximity Read ↗

RAD51 and RTEL1 compensate telomere loss in the absence of telomerase.Semantic proximity Read ↗

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