Article
Identification of a novel DRB1 allele, DRB1*1112, by sequence-based DRB typing.
Tissue antigens - 1 Jan 2001
Luo M, Blanchard J, Maclean I, Brunham R
Abstract excerpt
We report here a novel DRB1 allele (DRB1*1112) identified during sequence-based HLA-DRB typing. Polymerase chain reaction with generic DRB primers and group-specific primers and subsequent sequencing yielded identical results. Molecular cloning and sequencing confirmed that the new DRB1 allele is identical to DRB1*11011 and 1129 at exon 2 except for a single nucleotide substitution at codon 37, changing the codon...
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