Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Toxic multinodular goitre in a patient with generalized resistance to thyroid hormone who harbours the R429Q mutation in the thyroid hormone receptor beta gene.

Clinical endocrinology - 1 Jan 2001

Taniyama M, Ishikawa N, Momotani N, Ito K, Ban Y

Abstract excerpt

The association of resistance to thyroid hormone (RTH) due to a receptor defect with toxic multinodular goitre or with carcinoma of the thyroid has not been previously reported. Previous histopathological studies of the thyroid gland in patients with RTH have revealed changes similar to multinodular goitre, probably due to continuous stimulation by TSH. We report here a case of generalized resistance to thyroid...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Papillary, Follicular
Share to Goiter, Nodular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Receptors, Thyroid Hormone

Share to Sex Hormone-Binding Globulin

Share to Thyroid Neoplasms

Share to Thyroidectomy

Share to Thyroxine

Share to Triiodothyronine

Source

Identifiers

PMID: 11167935
DOI: 10.1046/j.1365-2265.2001.01033.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Toxic multinodular goitre in a patient with generalized resistance to thyroid hormone who harbours the R429Q mutation in the thyroid hormone receptor beta gene.PMID 11167935Read ↗

Pituitary resistance to thyroid hormone caused by a novel mutation (H435A) in the thyroid hormone receptor beta: A case report.Semantic proximity Read ↗

Thyroid hormone resistance in two patients with papillary thyroid microcarcinoma and their BRAFV600E mutation status.Semantic proximity Read ↗

A novel thyroid hormone receptor-beta mutation, not anticipated to occur in resistance to thyroid hormone, causes variable phenotypes.Semantic proximity Read ↗

Thyroid hormone resistance syndromes.Semantic proximity Read ↗

Resistance to thyroid hormone due to a novel thyroid hormone receptor mutant in a patient with hypothyroidism secondary to lingual thyroid and functional characterization of the mutant receptor.Semantic proximity Read ↗

Resistance to Thyroid Hormones: A Case-Series Study.Semantic proximity Read ↗

Thyroid hormone receptor beta gene mutation (P453A) in a family producing resistance to thyroid hormone.Semantic proximity Read ↗

Molecular pathogenesis of euthyroid and toxic multinodular goiter.Semantic proximity Read ↗

An overview of thyroid function tests in subjects with resistance to thyroid hormone and related disordersSemantic proximity Read ↗

Thyroid hormone resistance.Semantic proximity Read ↗

Genetic analysis of 29 kindreds with generalized and pituitary resistance to thyroid hormone. Identification of thirteen novel mutations in the thyroid hormone receptor beta gene.Semantic proximity Read ↗

Three novel mutations of thyroid hormone receptor beta gene in unrelated patients with resistance to thyroid hormone: two mutations of the same codon (H435L and H435Q) produce separate subtypes of resistance.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.