Article
Chemokine production by peripheral blood mononuclear cells in elderly subjects.
Mechanisms of ageing and development - 20 Dec 2000
Pulsatelli L, Meliconi R, Mazzetti I, Dolzani P, Meneghetti A, Neri S, Silvestri T, Ravaglia G, Forti P, Facchini A, Mariani E
Abstract excerpt
The function of chemokines in promoting and modulating leukocyte migration is essential for a prompt and efficacious inflammatory response and in host defence against infections. In order to investigate whether this important aspect of immunological response is influenced by ageing, we evaluated the basal levels as well as the ability of peripheral blood mononuclear cells from young and healthy elderly subjects...
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