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Article

Computational and experimental analyses reveal previously undetected coding exons of the KRIT1 (CCM1) gene.

Genomics - 1 Jan 2001

Sahoo T, Goenaga-Diaz E, Serebriiskii I G, Thomas J W, Kotova E, Cuellar J G, Peloquin J M, Golemis E, Beitinjaneh F, Green E D, Johnson E W, Marchuk D A

Abstract excerpt

A notable difficulty in annotating genomic sequence is identifying the correct start codon in a gene. An important such case has been found with KRIT1, the cerebral cavernous malformation type 1 (CCM1) gene. Analysis of human and mouse genomic sequence encompassing the region containing KRIT1/Krit1 using exon/gene-prediction and comparative alignment programs revealed putative exons upstream of the previously...

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Identifiers

PMID: 11161805
DOI: 10.1006/geno.2000.6426

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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