Article
Mechanisms for evolving hypervariability: the case of conopeptides.
Molecular biology and evolution - 1 Feb 2001
Conticello S G, Gilad Y, Avidan N, Ben-Asher E, Levy Z, Fainzilber M
Abstract excerpt
Hypervariability is a prominent feature of large gene families that mediate interactions between organisms, such as venom-derived toxins or immunoglobulins. In order to study mechanisms for evolution of hypervariability, we examined an EST-generated assemblage of 170 distinct conopeptide sequences from the venoms of five species of marine Conus snails. These sequences were assigned to eight gene families, defined...
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