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Article

Molecular and clinical differences between adenocarcinomas of the esophagus and of the gastric cardia.

The American journal of pathology - 1 Jan 2001

Tanière P, Martel-Planche G, Maurici D, Lombard-Bohas C, Scoazec J Y, Montesano R, Berger F, Hainaut P

Abstract excerpt

Adenocarcinoma of the esophagus (ADCE) with Barrett's mucosa and adenocarcinoma of the cardia (ADCC) are often reported as a single pathological entity. In this study we have used strict anatomical-pathological criteria to distinguish between these two lesions and we have investigated their differences in TP53 mutations, MDM2 gene amplification, and cytokeratin expression. DNA was extracted from the tumor areas...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 11141476
DOI: 10.1016/S0002-9440(10)63941-7
PMCID: PMC1850280

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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