Article
Thrombin generation in children with acute lymphoblastic leukemia: effect of leukemia immunophenotypic subgroups.
Pediatric hematology and oncology - 1 Dec 2000
Giordano P, Del Vecchio G C, Santoro N, Arcamone G, Coppola B, Altomare M, Schettini F, Iolascon A, De Mattia D
Abstract excerpt
Elevated plasma concentrations of endogenous thrombin generation markers and thrombotic events have been reported in children with leukemia. The aim of this study was to evaluate the effects of cancer and its treatment on thrombin generation (TAT levels) in children with acute lymphoblastic leukemia (ALL). The authors evaluated 32 children (23 M, 9 F) aged between 1 and 15 years (mean 6) affected by ALL...
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