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Article

Dopamine D4 receptor (DRD4) gene polymorphism is associated with attachment disorganization in infants.

Molecular psychiatry - 1 Nov 2000

Lakatos K, Toth I, Nemoda Z, Ney K, Sasvari-Szekely M, Gervai J

Abstract excerpt

About 15% of one-year-old infants in non-clinical, low-risk and up to 80% in high-risk (eg maltreated) populations show extensive disorganized attachment behavior(1,2) in the Strange Situation Test.(3) It has also been reported that disorganization of early attachment is a major risk factor for the development of childhood behavior problems.(4) The collapse of organized attachment strategy has been explained...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Dopamine D2

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Source

Identifiers

PMID: 11126393
DOI: 10.1038/sj.mp.4000773

Genes

DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Dopamine D4 receptor (DRD4) gene polymorphism is associated with attachment disorganization in infants.PMID 11126393Read ↗

Further evidence for the role of the dopamine D4 receptor (DRD4) gene in attachment disorganization: interaction of the exon III 48-bp repeat and the -521 C/T promoter polymorphisms.Semantic proximity Read ↗

DRD4 7-repeat polymorphism moderates the association between maternal unresolved loss or trauma and infant disorganization.Semantic proximity Read ↗

The interplay of birth weight, dopamine receptor D4 gene (DRD4), and early maternal care in the prediction of disorganized attachment at 36 months of age.Semantic proximity Read ↗

Association of D4 dopamine receptor gene and serotonin transporter promoter polymorphisms with infants' response to novelty.Semantic proximity Read ↗

The dopamine D4 receptor gene, birth weight, maternal depression, maternal attention, and the prediction of disorganized attachment at 36 months of age: A prospective gene×environment analysis.Semantic proximity Read ↗

No association of the dopamine D4 receptor (DRD4) and -521 C/T promoter polymorphisms with infant attachment disorganization.Semantic proximity Read ↗

The effects of child maltreatment and polymorphisms of the serotonin transporter and dopamine D4 receptor genes on infant attachment and intervention efficacy.Semantic proximity Read ↗

Transmission disequilibrium tests confirm the link between DRD4 gene polymorphism and infant attachment.Semantic proximity Read ↗

Genetic and environmental influence on attachment disorganization.Semantic proximity Read ↗

Infant genotype may moderate sensitivity to maternal affective communications: attachment disorganization, quality of care, and the DRD4 polymorphism.Semantic proximity Read ↗

Research Review: genetic vulnerability or differential susceptibility in child development: the case of attachment.Semantic proximity Read ↗

Adult attachment and gene polymorphisms of the dopamine D4 receptor and serotonin transporter (5-HTT).Semantic proximity Read ↗

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