Article
A common promoter variant of the leptin gene is associated with changes in the relationship between serum leptin and fat mass in obese girls.
Diabetes - 1 Dec 2000
Le Stunff C, Le Bihan C, Schork N J, Bougnères P
Abstract excerpt
Mutations in the leptin gene lead to rare obese syndromes of Mendelian inheritance in humans and rodents. However, no relevant mutations are found in the coding region of leptin gene DNA in patients with common multifactorial obesity. These obese patients tend to have an elevation of serum leptin...
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