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Apoptosis in fetal nucleated erythrocytes circulating in maternal blood

1 Jan 2000

Abstract excerpt

The purpose of this study was to determine if apoptosis occurs in fetal cells that have crossed into the maternal circulation, which would potentially explain the difference between the number of intact fetal cells and the amount of fetal DNA detectable in maternal plasma. We flow-sorted fetal nucleated erythrocytes (FNRBCs) using antibody to the gamma chain of fetal haemoglobin and confirmed them to be fetal in...

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PMID: 11113889
DOI: 10.1002/1097-0223(200011)20:11<886::aid-pd942>3.0.co;2-4

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