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Article

Cloning of a human tRNA isopentenyl transferase.

Gene - 27 Nov 2000

Golovko A, Hjälm G, Sitbon F, Nicander B

Abstract excerpt

A cDNA of human origin is shown to encode a tRNA isopentenyl transferase (E.C. 2.5.1.8). Expression of the gene in a Saccharomyces cerevisiae mutant lacking the endogenous tRNA isopentenyl transferase MOD5 resulted in functional complementation and reintroduction of isopentenyladenosine into tRNA. The deduced amino acid sequence contains a number of regions conserved in known tRNA isopentenyl transferases. The...

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Share to Alkyl and Aryl Transferases
Share to Cloning, Molecular
Share to Conserved Sequence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Complementary

Share to Genetic Complementation Test

Share to Saccharomyces cerevisiae

Share to Sequence Alignment

Share to Sequence Homology, Amino Acid

Source

Identifiers

PMID: 11111046
DOI: 10.1016/s0378-1119(00)00421-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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